Body Fluids and Circulation NEET PYQReal NEET & AIPMT 2005–2021 questions, year-tagged, with solutions
By the RankUp team, founded by Dr. Deepak Sahu (MBBS Gold Medalist, NEET PG AIR 1731) · Updated
Every Body Fluids and Circulation question from the NEET & AIPMT papers on this site (2005–2021), newest first. Each is tagged with its paper. Tap an option to check your answer and read the explanation.
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Body Fluids and Circulation previous year questions
42 questions. Tap an option to check your answer.
Q1NEET 2021
Persons with 'AB' blood group are called as "Universal recipients". This is due to :
Not quite — the answer is D.
People with AB blood have both A and B antigens on their RBCs and therefore make neither anti-A nor anti-B antibodies in plasma, so donor RBCs of any group are not attacked. The antigens are present, not absent, on their RBCs.
Q2NEET 2021
Which enzyme is responsible for the conversion of inactive fibrinogens to fibrins ?
Not quite — the answer is A.
Thrombin converts soluble inactive fibrinogen into fibrin threads that form the clot. Thrombokinase acts one step earlier, converting prothrombin into thrombin.
Q3NEET 2020 · Q75
The QRS complex in a standard ECG represents:
Not quite — the answer is C.
The QRS complex marks depolarisation of the ventricles, which starts ventricular contraction. The P wave is atrial depolarisation, the T wave is ventricular repolarisation, and atrial repolarisation is hidden in the QRS and has no separate wave.
Q4NEET 2020 · Q76
Match the following columns and select the correct option. Column - I | Column - II (a) Eosinophils | (i) Immune response (b) Basophils | (ii) Phagocytosis (c) Neutrophils | (iii) Release histaminase, destructive enzymes (d) Lymphocytes | (iv) Release granules containing histamine
Not quite — the answer is A.
Eosinophils resist infection and are linked to allergy (release of histaminase and destructive enzymes), basophils release granules with histamine, serotonin and heparin, neutrophils are phagocytic, and lymphocytes carry out immune responses. Hence histaminase, histamine, phagocytosis, immune response is correct.
Q5NEET 2019 · Q105
Match the Column - I with Column - II : (a) P - wave — (i) Depolarisation of ventricles (b) QRS complex — (ii) Repolarisation of ventricles (c) T - wave — (iii) Coronary ischemia (d) Reduction in the size of T - wave — (iv) Depolarisation of atria (v) Repolarisation of atria Select the correct option.
Not quite — the answer is A.
The P-wave is atrial depolarisation, the QRS complex is ventricular depolarisation and the T-wave is ventricular repolarisation. A reduced or flattened T-wave indicates coronary ischemia; atrial repolarisation is hidden in the QRS complex and is not matched to any wave.
Q6NEET 2019 · Q130
What would be the heart rate of a person if the cardiac output is 5 L, blood volume in the ventricles at the end of diastole is 100 mL and at the end of ventricular systole is 50 mL ?
Not quite — the answer is C.
Stroke volume = end-diastolic volume − end-systolic volume = 100 − 50 = 50 mL. Heart rate = cardiac output ÷ stroke volume = 5000 mL ÷ 50 mL = 100 beats per minute. Using the 72 beats/min resting value or dividing by 100 mL gives the wrong answer.
Q7NEET 2018 · Q137
Match the items given in Column I with those in Column II and select the correct option given below: Column I: a. Tricuspid valve, b. Bicuspid valve, c. Semilunar valve Column II: i. Between left atrium and left ventricle, ii. Between right ventricle and pulmonary artery, iii. Between right atrium and right ventricle
Not quite — the answer is C.
The tricuspid valve guards the opening between the right atrium and right ventricle, the bicuspid (mitral) valve lies between the left atrium and left ventricle, and a semilunar valve guards the exit from the right ventricle into the pulmonary artery. Swapping the tricuspid and bicuspid sides is the usual error.
Q8NEET 2018 · Q166
Match the items given in Column I with those in Column II and select the correct option given below: Column I: a. Fibrinogen, b. Globulin, c. Albumin Column II: i. Osmotic balance, ii. Blood clotting, iii. Defence mechanism
Not quite — the answer is D.
Fibrinogen is converted to fibrin during blood clotting, globulins (including antibodies) are mainly involved in the defence mechanisms of the body, and albumin maintains the osmotic balance of blood.
Q9NEET 2017 · Q70
The hepatic portal vein drains blood to liver from:
Not quite — the answer is D.
The hepatic portal vein carries blood from the intestine to the liver before it reaches the systemic circulation, so absorbed nutrients are processed first. Blood from the heart reaches the liver through the hepatic artery, and kidneys drain into the renal veins.
Q10NEET 2017 · Q74
Adult human RBCs are enucleate. Which of the following statement(s) is/are most appropriate explanation for this feature? (a) They do not need to reproduce (b) They are somatic cells (c) They do not metabolize (d) All their internal space is available for oxygen transport
Not quite — the answer is A.
Losing the nucleus leaves the whole biconcave cell free to be packed with haemoglobin, so it can carry the most oxygen. RBCs do metabolise (they run glycolysis), and being somatic or non-dividing does not explain why the nucleus is lost.
Q11NEET 2017 (Gujarati paper) · Q86
All the components of the conducting system can generate an action potential for the contraction of heart muscle, but the sino-atrial node acts as the pacemaker because:
Not quite — the answer is C.
The SA node generates the maximum number of action potentials per minute (about 70-75), so it sets the rhythm for the whole heart. Other nodal tissue such as the AV node is also autoexcitable but fires more slowly, so it is not true that only the SA node is autorhythmic.
Q12NEET 2017 (Gujarati paper) · Q111
In the heart, as the action potential reaches the AV node from the SA node, there is a delay of the action potential. This delay is important because:
Not quite — the answer is C.
The short AV-nodal delay lets the atria finish contracting and push their blood into the ventricles before ventricular systole begins. It does not make atrial contraction stronger or serve atrial filling from the venae cavae.
Q13NEET 2016 Phase 2 · Q152
Name the blood cells, whose reduction in number can cause clotting disorder, leading to excessive loss of blood from the body.
Not quite — the answer is D.
Thrombocytes (platelets) release factors needed for blood coagulation, so too few of them cause clotting disorders and heavy blood loss. Erythrocytes carry gases, and leucocytes, including neutrophils, are involved in defence.
Q14NEET 2016 Phase 2 · Q155
Serum differs from blood in
Not quite — the answer is C.
Serum is plasma from which the clotting factors such as fibrinogen have been removed by clotting. It still has albumins and globulins, including antibodies.
Q15NEET 2016 Phase 1 · Q161
Blood pressure in the pulmonary artery is:
Not quite — the answer is C.
The pulmonary artery receives blood pumped by the right ventricle, so its pressure (about 25/8 mm Hg) is higher than in the pulmonary vein returning blood to the left atrium. It is much lower than systemic arterial pressure in the aorta or carotid, and higher than in the venae cavae.
Q16AIPMT 2015
Which one of the following is correct?
Not quite — the answer is A.
Blood is plasma plus the formed elements: RBCs, WBCs and platelets. Serum is plasma without clotting factors, and lymph has no RBCs, so the other equations are wrong.
Q17AIPMT 2015
Blood pressure in the mammalian aorta is maximum during:
Not quite — the answer is D.
The left ventricle pumps blood into the aorta, so aortic pressure reaches its peak (systolic pressure, about 120 mm Hg) during left ventricular systole. Atrial contraction only tops up the ventricles and does not raise aortic pressure.
Q18AIPMT 2014
How do parasympathetic neural signals affect the working of the heart?
Not quite — the answer is D.
Parasympathetic (vagal) signals slow the SA node and AV conduction, so heart rate falls and with it the cardiac output. Increases in heart rate or cardiac output are caused by sympathetic stimulation, not parasympathetic.
Q19AIPMT 2014
Person with blood group AB is considered as universal recipient because he has:
Not quite — the answer is D.
A person with AB blood has both A and B antigens on the RBCs and no anti-A or anti-B antibodies in the plasma, so donor RBCs of any ABO group are not agglutinated. Antigens are on the RBC surface, not in plasma, and group O (not AB) has no antigens.
Q20AIPMT 2012 Mains
Which one of the following human organs is often called the "graveyard" of RBCs?
Not quite — the answer is C.
The spleen filters the blood and destroys old, worn-out RBCs, earning the name 'graveyard of RBCs'. The liver breaks down haemoglobin products but is not the organ called the graveyard.
Q21AIPMT 2012 Prelims
A certain road accident patient with unknown blood group needs immediate blood transfusion. His one doctor friend at once offers his blood. What was the blood group of the donor ?
Not quite — the answer is D.
Blood group O has no A or B antigens on its RBCs, so it can be given to a patient of any ABO group; O is the universal donor. Group AB is the universal recipient, not donor.
Q22AIPMT 2012 Prelims
Compared to those of humans, the erythrocytes in frog are
Not quite — the answer is C.
Frog erythrocytes are nucleated and contain haemoglobin, unlike the enucleate RBCs of mammals. They are also larger, not smaller, than human RBCs.
Q23AIPMT 2011 Mains
Frogs differ from humans in possessing
Not quite — the answer is A.
Frog RBCs are nucleated, while mature human RBCs lack a nucleus. Both frogs and humans have thyroid and parathyroid glands, paired cerebral hemispheres and a hepatic portal system.
Q24AIPMT 2011 Prelims
A person with unknown blood group under ABO system, has suffered much blood loss in an accident and needs immediate blood transfusion. His one friend who has a valid certificate of his own blood type, offers for blood donation without delay. What would have been the type of blood group of the donor friend?
Not quite — the answer is D.
Blood group O red cells carry neither the A nor the B antigen, so they are not agglutinated by the recipient's antibodies: O is the universal donor. Since the patient's group is unknown, only O blood can safely be given without delay; AB is the universal recipient, not donor.
Q25AIPMT 2011 Prelims
Arteries are best defined as the vessels which
Not quite — the answer is C.
An artery is defined by the direction of flow: it carries blood away from the heart to the organs. Not all arteries carry oxygenated blood (the pulmonary artery carries deoxygenated blood), so oxygen content does not define them.
Q26AIPMT 2011 Prelims
'Bundle of His' is a part of which one of the following organs in humans?
Not quite — the answer is C.
The bundle of His (AV bundle) is part of the conducting system of the heart: it arises from the AV node, runs through the interventricular septum and divides into right and left bundle branches.
Q27AIPMT 2011 Prelims
Which of the following plasma proteins is involved in the coagulation of blood?
Not quite — the answer is A.
Fibrinogen is the plasma protein converted by thrombin into fibrin threads, which form the network of a clot. Albumins maintain osmotic balance and globulins serve in defence; amylase is an enzyme, not a clotting factor.
Q28AIPMT 2011 Prelims
Which one of the following statements is correct regarding blood pressure?
Not quite — the answer is A.
Normal blood pressure is about 120/80 mmHg, and repeated readings of 140/90 or higher indicate hypertension. A pressure of 190/110 mmHg is severe and can damage vital organs such as the brain and kidneys. Readings like 100/55 or 105/50 are on the low side, not ideal or energising.
Q29AIPMT 2010 Mains · Q3
Fastest distribution of some injectible material/medicine and with no risk of any kind can be achieved by injecting it into the
Not quite — the answer is C.
An intravenous injection puts the drug straight into venous blood, which returns to the heart and is pumped all over the body within seconds. Arteries carry blood at high pressure, so puncturing them is risky, and intramuscular injection only releases the drug slowly from the muscle. Lymph flow is very slow.
Q30AIPMT 2010 Mains · Q25
Given below are four statements (a-d) regarding human blood circulatory system (a) Arteries are thick-walled and have narrow lumen as compared to veins (b) Angina is acute chest pain when the blood circulation to the brain is reduced (c) Persons with blood group AB can donate blood to any person with any blood group under ABO system (d) Calcium ions play a very important role in blood clotting Which two of the above statements are correct?
Not quite — the answer is A.
Arteries have thick muscular walls and a narrow lumen compared with veins, and Ca²⁺ ions are needed at several steps of the clotting cascade. Angina is chest pain caused by too little oxygen reaching the heart muscle, not the brain, and AB individuals are universal recipients, while O is the universal donor.
Q31AIPMT 2010 Mains · Q27
The haemoglobin content per 100 ml of blood of a normal healthy human adult is
Not quite — the answer is D.
NCERT states that a healthy adult has 12-16 g of haemoglobin in every 100 ml of blood. Values of 5-11 g would indicate anaemia, and 17-20 g or more are above the normal range.
Q32AIPMT 2010 Prelims · Q146
If due to some injury the chordae tendinae of the tricuspid valve of the human heart is partially non-functional, what will be the immediate effect?
Not quite — the answer is A.
Chordae tendineae stop the tricuspid valve from turning inside out during ventricular systole. If they fail, part of the right ventricle's blood leaks back into the right atrium, so less is pumped into the pulmonary artery. The left atrium is on the other side of the heart (the bicuspid valve), so backflow there is not the effect.
Q33AIPMT 2009 Prelims · Q70
The most popularly known blood grouping is the ABO grouping. It is named ABO and not ABC, because O in it refers to having:
Not quite — the answer is C.
Group O red cells carry neither antigen A nor antigen B on their surface, so 'O' stands for the absence (zero) of these antigens. The O allele is recessive, not overdominant, and antibodies are in the plasma, not on the RBCs.
Q34AIPMT 2009 Prelims · Q76
Compared to blood our lymph has:
Not quite — the answer is B.
Lymph is tissue fluid drained into lymphatic vessels; it has no RBCs and is rich in lymphocytes (WBCs). It does contain plasma with fewer proteins, so 'plasma without proteins' and 'no plasma' are wrong.
Q35AIPMT 2009 Prelims · Q117
In a standard ECG which one of the following alphabets is the correct representation of the respective activity of the human heart?
Not quite — the answer is C.
In an ECG the P-wave represents electrical excitation (depolarisation) of the atria, leading to atrial contraction. The QRS complex is ventricular depolarisation and the T-wave is ventricular repolarisation, so R is not repolarisation.
Q36AIPMT 2009 Prelims · Q130
Globulins contained in human blood plasma are primarily involved in:
Not quite — the answer is D.
NCERT states that globulins are primarily involved in the defence mechanisms of the body (antibodies are gamma globulins). Albumins maintain osmotic balance and fibrinogen helps in clotting.
Q37AIPMT 2008 Prelims · Q144
Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin?
Not quite — the answer is C.
Basophils secrete histamine, serotonin and heparin and take part in inflammatory reactions, as NCERT states. Eosinophils resist infections and are linked to allergies but are not the source of heparin.
Q38AIPMT 2008 Prelims · Q155
The most active phagocytic white blood cells are
Not quite — the answer is A.
NCERT states that neutrophils and monocytes (which become macrophages) are phagocytic cells that destroy foreign organisms. Lymphocytes are responsible for immune responses, not phagocytosis.
Q39AIPMT 2008 Prelims · Q157
In humans, blood passes from the post caval to the diastolic right atrium of heart due to
Not quite — the answer is A.
During atrial diastole the pressure in the right atrium falls below that in the venae cavae, so blood flows down this pressure gradient into the atrium. SA node stimulation starts contraction (systole), not the filling of a relaxed atrium.
Q40AIPMT 2007 Prelims · Q105
If you suspect major deficiency of antibodies in a person, to which of the following would you look for confirmatory evidence?
Not quite — the answer is A.
Antibodies are immunoglobulins, which belong to the globulin fraction of plasma proteins, so a low serum globulin level would confirm antibody deficiency. Albumins mainly maintain osmotic balance and fibrinogen is a clotting protein, so neither reflects antibody levels.
Q41AIPMT 2007 Prelims · Q167
A drop of each of the following, is placed separately on four slides. Which of them will not coagulate?
Not quite — the answer is A.
Serum is plasma from which fibrinogen and other clotting factors have been removed, so it cannot clot. Plasma, whole blood and lymph still contain fibrinogen and will coagulate.
Q42AIPMT 2005 Prelims · Q128
Which of the following substances, if introduce in the blood stream, would cause coagulation, at the site of its introduction ?
Not quite — the answer is D.
Thromboplastin (tissue factor) starts the clotting cascade, which leads to thrombin formation and turns fibrinogen into fibrin, so a clot forms where it is introduced. Fibrinogen and prothrombin already circulate in plasma without clotting, and heparin is an anticoagulant.
How often Body Fluids and Circulation came up
Questions from this chapter in each paper on this site.
- NEET 2021: 2
- NEET 2020: 2
- NEET 2019: 2
- NEET 2018: 2
- NEET 2017: 2
- NEET 2017 (Gujarati paper): 2
- NEET 2016 Phase 2: 2
- NEET 2016 Phase 1: 1
- AIPMT 2015: 2
- AIPMT 2014: 2
- AIPMT 2012 Mains: 1
- AIPMT 2012 Prelims: 2
- AIPMT 2011 Mains: 1
- AIPMT 2011 Prelims: 5
- AIPMT 2010 Mains: 3
- AIPMT 2010 Prelims: 1
- AIPMT 2009 Prelims: 4
- AIPMT 2008 Prelims: 3
- AIPMT 2007 Prelims: 2
- AIPMT 2005 Prelims: 1
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